Products Description of Piroctone Olamine CAS 68890-66-4
Piroctone olamine (INN), alternatively named piroctone ethanolamine and commercially known as Octopirox, has molecular formula C16H30N2O3 and molecular weight of 298.43. Chemically, it corresponds to the ethanolamine salt of piroctone, a derivative belonging to the hydroxamic acid family. It is white to pale yellow crystalline powder with faint characteristic odor.
This cosmetic-grade active ingredient melts at 134–138°C, freely soluble in ethanol and chloroform, while sparingly soluble in water. It remains stable under neutral and weakly alkaline conditions. It is widely recognized as an effective anti-dandruff and antifungal raw material for hair care formulations.
Piroctone Olamine Chemical Properties
| Melting point | 134.0 to 138.0 °C |
| Boiling point | 135-235℃[at 101 325 Pa] |
| density | 1.1[at 20℃] |
| vapor pressure | 0-0Pa at 20-25℃ |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly, Sonicated), Methanol (Slightly) |
| pka | 5.9-7.4[at 20 ℃] |
| form | Solid |
| color | White to Off-White |
| Water Solubility | 400-50000mg/L at 20-25℃ |
| Merck | 147502 |
| Major Application | agriculture |
| environmental | |
| Cosmetics Ingredients Functions | PRESERVATIVE |
| ANTI-SEBORRHEIC | |
| InChI | InChI=1S/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5; 3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2 |
| InChIKey | BTSZTGGZJQFALU-UHFFFAOYSA-N |
| SMILES | C(N)CO.C(C1=CC(C)=CC(=O)N1O)C(C)CC(C)(C)C |
| LogP | 1.05-3.86 at 20-25℃ |
| CAS DataBase Reference | 68890-66-4(CAS DataBase Reference) |
| WGK Germany | 2 |
| RTECS | UU7786150 |
| HS Code | 2933399090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Aquatic Chronic 3 |
| Eye Dam. 1 | |
| Skin Irrit. 2 |
Product Applications of Piroctone Olamine CAS 68890-66-4
Piroctone Olamine is a popular cosmetic active ingredient with broad-spectrum antifungal and antibacterial properties. Its primary application is as a mild anti-dandruff agent for hair care, added into anti-dandruff shampoo, conditioner, scalp tonic and leave-on scalp serums to relieve itching, reduce flaking and regulate scalp sebum. It is also applied in skincare formulas such as facial cleansers, body washes and anti-acne gels for fungal-related skin issues.
Besides hair and skin care, it can serve as auxiliary preservative in cosmetic formulations, and used in deodorants and foot care products to inhibit microbes. This raw material is widely accepted in global cosmetic markets and compatible with most surfactant systems.
