3-Chloro-2-hydroxypropyltrimethyl ammonium chloride CAS#3327-22-8

High Cationizing Efficiency: Its highly reactive epoxy-forming group enables rapid and complete introduction of quaternary ammonium groups onto starch, cellulose and guar gum substrates.

Broad Substrate Compatibility: It works effectively with polysaccharides, synthetic polymers and fibers, producing cationic derivatives for diverse industrial applications.

Enhanced End Product Performance: Cationic derivatives prepared with CHPTAC deliver improved charge neutralization, adsorption, flocculation and conditioning properties in papermaking, textiles and personal care.

Stable and Easy to Use: The stable 65% aqueous solution allows accurate dosing and simple handling in production, ensuring consistent quality and convenient process control.

Products Description of 3-Chloro-2-hydroxypropyltrimethyl ammonium chloride CAS#3327-22-8

3-Chloro-2-hydroxypropyltrimethyl ammonium chloride, commonly abbreviated as CHPTAC, is a cationic quaternary ammonium reagent with a molecular formula of C6H15Cl2NO and a molecular weight of 188.10. It is commercially supplied as a colorless to light yellow clear aqueous solution, typically with an active content of about 65%. The product has a density of approximately 1.154 g/mL and is fully miscible with water. 

As a highly reactive cationic etherifying agent, CHPTAC is widely used to introduce quaternary ammonium groups onto starch, cellulose and guar gum, thereby producing cationic derivatives applied in papermaking, textile finishing, personal care and water treatment. 

3-Chloro-2-hydroxypropyltrimethyl ammonium chloride CAS#3327-22-8

3-Chloro-2-hydroxypropyltrimethyl ammonium chloride Chemical Properties

Melting point 191-193°C
density 1.154 g/mL at 25 °C
vapor pressure 0.001Pa at 20℃
refractive index n20/D 1.4541
Fp >230 °F
storage temp. Sealed in dry,Room Temperature
solubility Methanol (Slightly), Water (Sparingly)
form clear liquid
color Colorless to Light yellow
PH4.8 to 6.4(50g/L, 25℃)
Water Solubility 835.2g/L at 20℃
BRN 6576172
InChIInChI=1S/C6H15ClNO.ClH/c1-8(2,3)5-6(9)4-7;/h6,9H,4-5H2,1-3H3;1H/q+1;/p-1
InChIKeyCSPHGSFZFWKVDL-UHFFFAOYSA-M
SMILES[N+](C)(CC(O)CCl)(C)C.[Cl-]
LogP-1.5 at 25℃
CAS DataBase Reference3327-22-8(CAS DataBase Reference)
EPA Substance Registry System3-Chloro-2-hydroxypropyltrimethyl ammonium chloride (3327-22-8)
Hazard Codes Xn
Risk Statements 36/37/38-52/53-40
Safety Statements 26-36-61-36/37
RIDADR 2811
WGK Germany 2
RTECS BP5275400
HS Code 2923.90.0100
HazardClass 6.1(b)
PackingGroup III
ToxicityLDLo subcutaneous in mouse: 500mg/kg
3-Chloro-2-hydroxypropyltrimethyl ammonium chloride CAS#3327-22-8

Product Application of 3-Chloro-2-hydroxypropyltrimethyl ammonium chloride CAS#3327-22-8

CHPTAC acts as a versatile cation-active auxiliary across multiple manufacturing sectors.

Paper-making sector. It modifies starch, cellulose and its derived substances via etherification. The yielded cation-modified starch can work as paper-strengthening additive, internal sizing binder, filler and retention agent for tiny fibre fragments.

Textile processing field. After reacting with cotton fibre, it improves the adhesive capacity of dyestuffs. Its modified cationic starch also serves as the sizing substance for warp threads.

Water-purification industry. Suspended particulate contaminants in water carry negative surface charges. Cation-rich polymers prepared with this raw-material function as flocculants for water treatment.

Personal-care chemical sector. It helps synthesize cationic guar gum and other ether-modified derivatives, which constitute essential raw-materials for everyday-use chemical commodities.

3-Chloro-2-hydroxypropyltrimethyl ammonium chloride CAS#3327-22-8

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