Product Description of Isopropylamine CAS#75-31-0
As a vital low-carbon aliphatic-amine organic substance, isopropylamine bears the chemical formula C₃H₉N with a molecular weight of 59.11. Under normal-temperature and atmospheric-pressure circumstances, it is a volatile colour-free liquid emitting a pungent ammonia-like odour, and its aqueous solution features strong alkalinity. The substance is miscible with water, ethanol as well as diethyl ether, and shows high solubility inside acetone. Classified as a regulated hazardous chemical, isopropylamine carries substantial risks, hence rigorous protective measures are required throughout handling operations.
Isopropylamine Chemical Properties
| Melting point | -95.2 °C |
| Boiling point | 32-34 °C (760mmHg) |
| density | 0.688 g/mL at 20 °C (lit.) |
| vapor density | 2.04 (vs air) |
| vapor pressure | 9.2 psi ( 20 °C) |
| FEMA | 4238 | ISOPROPYLAMINE |
| refractive index | n20/D 1.374(lit.) |
| Fp | -26 °C |
| storage temp. | 15-25℃ |
| solubility | Miscible with water |
| form | Liquid |
| pka | 10.63(at 25℃) |
| color | Colorless |
| Odor | Strong ammoniacal; pungent, irritating, typical amine. |
| PH | 13 (700g/l, H2O, 20℃) |
| explosive limit | 2-10.4%(V) |
| Odor Threshold | 0.025ppm |
| Odor Type | fishy |
| Water Solubility | Fully miscible in water |
| Sensitive | Moisture sensitive, volatile |
| JECFA Number | 1581 |
| Merck | 145209 |
| BRN | 605259 |
| Exposure limits | TLV-TWA 5 ppm (～12 mg/m3) (ACGIH, MSHA, and OSHA); TLV-STEL 10 ppm(～24 mg/m3) (ACGIH); IDLH 4000 ppm (NIOSH). |
| Dielectric constant | 5.5（20℃） |
| Stability: | Stable. Extremely flammable - note low boiling point and low flash point. Readily forms explosive mixtures with air. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, perchloryl fluoride. |
| LogP | 0.21 |
| CAS DataBase Reference | 75-31-0(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Propanamine(75-31-0) |
| EPA Substance Registry System | Isopropylamine (75-31-0) |
Safety Information
| Hazard Codes | F+,Xi,T |
| Risk Statements | 12-36/37/38-37-35-25-20/21 |
| Safety Statements | 16-26-29-45-36/37/39 |
| RIDADR | UN 1221 3/PG 1 |
| WGK Germany | 1 |
| RTECS | NT8400000 |
| F | 34 |
| Autoignition Temperature | 755 °F |
| TSCA | Yes |
| HS Code | 2921 19 99 |
| HazardClass | 3 |
| PackingGroup | I |
| Hazardous Substances Data | 75-31-0(Hazardous Substances Data) |
| Toxicity | LD50 orally in rats: 820 mg/kg (Smyth) |
| IDLA | 750 ppm |
Product Application of Isopropylamine CAS#75-31-0
Isopropylamine functions as a versatile solvent and a critical foundational material for organic synthesis processes. It acts as a core chemical intermediate for manufacturing a broad spectrum of products, including agrochemicals, pharmaceutical substances, dye intermediates, rubber vulcanization accelerators, emulsifiers, detergents and depilatory agents. Additionally, it is widely applied in the production of hard water conditioners, surfactants and textile auxiliary additives.
In the agrochemical sector, this compound participates in the synthesis of multiple pesticides. It is utilized to produce Badan, as well as herbicides like atrazine and ametryn, and the insecticide cypermethrin. For pharmaceutical manufacturing, it serves as a vital synthetic raw material for galactopyranoside derivatives, indole hydrochloride, propranolol hydrochloride and indole propranolol, supporting the preparation of various medicinal compounds.
